site stats

K14-cre

Webb7 aug. 2024 · 2.1 新的Cre品系需要做的四件事:. 1) 了解小鼠来源,背景信息及发表的文章;. 2) 建立基因型鉴定方法,确认小鼠正确;. 3) 验证Cre在目标组织中的表达. 4) 验证Cre的敲除效率. 了解小鼠来源,背景信息及发表的文章. Mouse Genome Informatics CrePortal :. 在Recombinase (cre)中 ... Webb27 juni 2024 · Our previous study using K14-Cre;R26R mice demonstrated intense β-gal-positivity (an indicator for Cre activity) among the cells at the epithelium overlying the palatal process of the secondary and primary palates (Sarper et al., 2024). This was also evident in the contacting and fused epithelium in anterior palatogenesis.

018964 - Strain Details - The Jackson Laboratory

Webb26 sep. 2016 · Here we developed mouse models based on the gene TNIP1, whose loss-of-function in humans is linked to psoriasis. Based on these models, we provide evidence that nonimmune cells, specifically skin-resident … Webb3 juli 2008 · Here we show that slow-cycling cells appear early in skin development, express SC markers, and later give rise to the adult SC population. To test whether these early slow-cycling cells function as SCs, we use Sox9-Cre for genetic marking and K14-Cre to embryonically ablate Sox9, an essential adult SC gene. bismarck fire inspection https://zukaylive.com

Tg(KRT14-cre)1Amc Transgene Detail MGI Mouse (MGI:2445832)

http://m.ebiotrade.com/newsf/2024-6/2024610122937904.htm WebbWe have found previously that this phenotype does not depend on the presence of alphabeta T lymphocytes. In order to evaluate contributions of other immune cell populations to the skin disease, we selectively eliminated macrophages and granulocytes from the skin of mice with epidermis-specific deletion of IKK2 (K14-Cre-IKK2fl/fl mice). http://www.informatics.jax.org/allele/MGI:1926500 bismarck fireworks

IFT140+/K14+ cells function as stem/progenitor cells in salivary …

Category:An RNA interference screen uncovers a new molecule in stem cell …

Tags:K14-cre

K14-cre

Kry

Webb17 maj 2024 · Deletion of Mettl3 in epidermal progenitors leads to taste bud defects. As previously described, basal progenitors develop into taste cells (K8) and differentiated keratinocytes (K13) (Fig. (Fig.1a 1a) 15,16,40.To explore whether deletion of Mettl3 affected taste bud development, we crossed Mettl3 fl/fl mice 28 with K14-Cre … WebbK14-Cre小鼠与FloxP小鼠交配后,在Cre特异表达的组织或者器官或细胞中,两个FloxP位点间的外显子或元件将被删除,达到条件性敲除或过表达的目的。可用于皮肤等相关研究。

K14-cre

Did you know?

WebbFig1 体视显微镜检测Krt14-CreERT2 +/-; Rosa26 tdTomato +/- 小鼠皮肤(Skin)、舌(Tongue)及食管(Esophagus)中tdTomato的表达。. 结果显示:Krt14-CreERT2 … WebbK14-Cre小鼠. 分类: Cre鼠 发布时间: 2024-07-11 11:00. 应用:皮肤. 级别:SPF. 类型:TG/KI. 背景:C57BL/6. 该Cre小鼠与FloxP小鼠交配后,在Cre特异表达的组织或者器 …

Webb22 nov. 2024 · The primary cilium is a solitary, sensory organelle that extends from the surface of nearly every vertebrate cell, including craniofacial cells. This organelle converts chemical and physical external stimuli into intracellular signaling cascades and mediates several well-known signaling pathways simultaneously. Thus, the primary cilium is … Webb15 jan. 2009 · Re-epithelialization after skin wounding requires both migration and hyperproliferation of keratinocytes. Laminin-332 is deposited during migration over the provisional matrix. To investigate the function of the laminin-332 binding integrin α3β1 in wound re-epithelialization, we generated Itga3flox/flox; K14-Cre mice lacking the α3 …

WebbThese K14-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in the ectoderm and its derivatives (including the skin, dental epithelium, and oral … Webb27 dec. 2024 · View Tg(KRT14-cre)1Amc allele: origin, molecular description and human disease models, images, gene associations, and references. Home; Genes; Phenotypes; Human Disease; ... K14cre, K14 cre, K14-cre, Krt14 Cre: Transgene: Tg(KRT14-cre)1Amc Location: unknown Alliance: Tg(KRT14-cre)1Amc page Transgene origin: …

WebbArticle Snippet: Mice expressing Cre recombinase under control of the human keratin 14 (K14) promoter ( Krt14-Cre ) [stock no. 004782, STOCK Tg( KRT14-Cre )1Amc/J] ( 35 ) and mice carrying loxP sites flanking exon 6 of Rptor (stock no. 013188, B6.Cg- Rptor tm1.1Dmsa /J) ( 37 ) were from The Jackson Laboratory.

WebbThe hyperproliferative, inflammatory skin disease in K14-Cre-IKK2fl/fl mice was a direct consequence of the presence of macrophages in the skin, as targeted deletion of … darling hall hearing clinicWebbKlicka på Logga in, och identifiera dig med ditt Mobila BankID. Om du inte har använt Kry-appen förut måste du registrerar dig som användare genom att ange telefonnummer … darling hall outprocessingWebb10 okt. 2024 · The phenotype of SMGs in developing and mature Ift140-cKO mice. a By mating Ift140flox/flox mice with K14-cre mice, Ift140 was selectively knocked out from K14 + cells. b The appearance of the... darling hall fort gordon outprocessingWebb19 juli 2024 · We also generated k14-cre; Sox2 fl/fl mice to explore the function of Sox2 during mouse incisor development. And this K14cre-driven recombination activates at around 11.75, which is much later than the Shh-cre and Pitx2-cre. And k14-cre; Sox2 fl/fl mice can survive and grow up with normal incisor morphogenesis (data not shown). bismarck flight awareWebbInsertion. Mutation details : Expression of Cre recombinase in the basal layer of the epidermis, the outer root sheath of the hair follicle and the oral epithelium, driven by the human keratin 14 promoter/enhancer (KRT14). Promoter is active by embryonic day 14.5 (E14.5). ( J:56822 ) bismarck first namehttp://www.informatics.jax.org/allele/MGI:1926500 bismarck fire departmentbismarck first day of school 2022