Dna ligands for aflatoxin and zearalenone

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August undefined, 2024

WebDNA LIGANDS FOR AFLATOXIN AND ZEARALENONE United States Application US20120245494 Note: If you have problems viewing the PDF, please make sure you have the latest version of Adobe Acrobat . Back to full text WebAflatoxin B1-DNA adduct formation and mutagenicity in livers of neonatal male and female B6C3F1 mice. Exposure to genotoxic chemicals at a young age increases cancer incidence later in life. Aflatoxin B(1) (AFB(1)) is a potent genotoxin that induces hepatocellular carcinoma (HCC) in many animal species and in humans.

EP2467483A1 - Dna ligands for aflatoxin and zearalenone - Google

WebDec 1, 2016 · Aflatoxins are naturally occurring mycotoxins that contaminate food and agro commodities, leading to acute and chronic health conditions in human and animals. In the present work, an attempt was made to generate high-affinity single stranded DNA aptamers that specifically bind to Aflatoxin B1 (AFB1) by a modified Systemic Evolution of … Webzearalenone aflatoxin dna ligands ligands dna Prior art date 2009-08-21 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Withdrawn Application number EP10809412.9A Other languages English (en) French (fr) cake meme gif

(19) United States (12) Patent Application Publication (10) …

WebDec 14, 2024 · It consist of six consecutive steps; viz. (i) the mutation of the DNA sequence of residues to RNA, (ii) annealing process of the RNA structure using SimRNA, (iii) performance of Monte Carlo... WebMar 8, 1999 · Aflatoxin B1 (AFB1), a category I known human carcinogen and the most potent genotoxic agent, is mutagenic in many model systems and produces chromosomal aberrations, micronuclei, sister chromatid exchange, unscheduled DNA synthesis, and chromosomal strand breaks, as well as forms adducts in rodent and human cells. WebSep 1, 2024 · Aflatoxin B 1 and zearalenone were simultaneously determined with high selectivity. Abstract Mycotoxins contamination in agricultural products poses a serious threat to human and animal health, so rapid and sensitive nanosensors for simultaneous determination of multiple mycotoxins in food samples are highly desirable for food safety … cake menu background design

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EP 2467483 A1 20120627 - DNA LIGANDS FOR …

WebOct 24, 2024 · Notably, St MCO could directly degrade aflatoxin B 1 (AFB 1) and zearalenone (ZEN) in the absence of mediators. Meanwhile, the presence of various lignin unit-derived natural mediators or ABTS could significantly accelerate the degradation of AFB 1 and ZEN by St MCO. WebEurope PMC is an ELIXIR Core Data Resource Learn more >. Europe PMC is a service of the Europe PMC Funders' Group, in partnership with the European Bioinformatics Institute ; and in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine (NCBI/NLM) . It includes content provided to the PMC ... cake mediterranã©enWebSep 15, 2024 · Aptamers are single strand oligonucleotides selected in vitro by Systematic Evolution of Ligands by Exponential ... Simultaneous detection of aflatoxin B1, ochratoxin A, zearalenone and deoxynivalenol in corn and wheat using surface plasmon resonance ... G.A. Penner, DNA ligands for aflatoxin and zearalenone, US patent … cake menu template free download

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Dna ligands for aflatoxin and zearalenone

WebJun 15, 2014 · Ochratoxin A (OTA), zearalenone (ZEN), α-zearalenol, and aflatoxin M1 (AFM 1) were purchased from Sigma-Aldrich (USA). Aflatoxin B 2 (AFB 2 ), aflatoxin G 1 (AFG 1 ), aflatoxin G 2 (AFG 2), and fumonisin (FB1) were purchased from Pribolab Co. Ltd (Singapore). Streptavidin was obtained from Sangon Biotechnology Co. Ltd. (Shanghai, … Web核酸适配体既可以是RNA也可以是DNA，广泛应用在食品安全检测中作为危害因子的特异性分子识别元件，在物质分离富集过程中作为能够与靶目标发生特异性结合的配基以及在医学上用于临床诊断和治疗。 ... 指数富集配基系统进化技术（Systematic Evolution Of Ligands by ...

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WebNov 1, 2024 · Anti-idiotypic nanobody-phage display-mediated real-time immuno-PCR for sensitive, simultaneous and quantitative detection of total aflatoxins and zearalenone in grains Anti-idiotypic nanobody-phage display-mediated real-time immuno-PCR for sensitive, simultaneous and quantitative detection of total aflatoxins and zearalenone in grains … Webzearalenone aflatoxin dna ligands ligands dna Prior art date 2009-08-21 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Withdrawn Application number EP10809412.9A Other languages German (de) French (fr)

WebApr 15, 2024 · 1. Introduction. Mycotoxins are secondary metabolites of fungi. At present, about 400 mycotoxins have been identified and a dozen have been confirmed harmful to humans and animals, such as aflatoxin, ochratoxin, fumonisin, zearalenone, patulin and so on [1].Among them, aflatoxin is considered as one of the most significant mycotoxins … WebA method for the identification of DNA ligands that bind to Zea characterized in that the method comprises: (a) contacting a random library of single stranded DNA sequences to immobilized Zea under...

WebThe invention relates also to methods for determining the presence and concentration of aflatoxin and zearalenone in samples such as agricultural and food products, and to methods for removing or... WebThe present invention relates to DNA ligands capable of binding to aflatoxin and zearalenone. The invention relates also to methods for determining the presence and concentration of aflatoxin and zearalenone in samples such as agricultural and food products, and to methods for removing or reducing the level of aflatoxin and zearalenone …

WebAug 20, 2010 · The present invention relates to DNA ligands capable of binding to aflatoxin and zearalenone. The invention relates also to methods for determining the presence and concentration of aflatoxin and zearalenone in samples such as agricultural …

WebPreviously, we designed five new aptamers to aflatoxin B 1 (AFB1) based on a known aptamer sequence (Patent: PCT/CA2010/001 292, Apt1) through a genetic algorithm-based in silico maturation strategy and experimentally measured their affinity to the target toxin. Here, integrated molecular dynamic simulation (MDs) studies with molecular ... cake menu template freeWebMay 11, 2012 · DNA2链的NaCl浓度为300mmol/L，此时的孵化率为30.6%。本实验中加入SDS的主要作用一是增加纳米金的稳定性，降低其对管壁的吸附性；二是缩短了实验时间，以前的孵化一般都要在48h以上，本实验只需10多个小时；三是在维持纳米金颜色不变的同时增加了NaCl的浓度，进而增加了纳米金表面DNA的附着量，这对于以纳米金和DNA链 … cake menus and pricesWebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. cake me homeWebJun 8, 2013 · Zearalenone (ZEN) is a nonsteroidal estrogenic mycotoxin produced by Fusarium graminearum on maize and barley. Because most current methods of ZEN detection rely on the use of low-stability antibodies or expensive equipment, we sought to develop a rapid, low-cost determination method using aptamers instead of antibodies as … cng to usdWebAug 9, 2024 · Le CL, Cruz-Aguado JA, Penner GA (2012) DNA ligands for aflatoxin and zearalenone. United State Patent No. US20120245494A1. ... Li Y, Lu Y, Xiong X, Li Y, Liu Y, Lu L (2024) Sensitive electrochemical detection of aflatoxin B1 using DNA tetrahedron nanostructure as substrate of antibody ordered assembly and template of aniline … cake merchant campbelltownWebAug 20, 2010 · The present invention relates to DNA ligands capable of binding to aflatoxin and zearalenone. The invention relates also to methods for determining the presence and concentration of aflatoxin and zearalenone in samples such as agricultural and food products, and to methods for removing or reducing the level of aflatoxin and … cng to idrWebNov 9, 2024 · Notably, S.DNAzyme cross-reacted with three other tested aflatoxins, including aflatoxin B2, aflatoxin G1 and aflatoxin M1, revealing the potential for a broadly applicable method to identify the family of aflatoxins. cng tax credits